Nitrous oxide (laughing gas) is contraindicated in pneumothorax, small bowel obstruction, middle ear surgery, and retinal surgeries involving the creation of an intraocular gas space / bubble. Reference: NCBI, StatPearls: https://www.ncbi.nlm.nih.gov/books/NBK532922/#:~:text=Thus%20nitrous%20oxide%20is%20contraindicated,of%20an%20intraocular%20gas%20bubble.
